When protecting trees and shrubs from common pests, choose products that target the insects most likely to attack your landscape while supporting plant health. This guide highlights five effective options and explains who benefits most from each. It’s ideal for homeowners and semi-professional landscapers seeking long-lasting protection without complex applications.
The table below compares key traits to simplify your decision. All products are designed for outdoor use on trees and shrubs and offer varying durations of protection and levels of systemic action.
| Product | Best For | Protection Duration |
|---|---|---|
| BioAdvanced Tree & Shrub Insect Killer (32 oz) | Light to moderate infestations on ornamentals and small trees | Up to 2 weeks per application |
| BioAdvanced 12 Month Tree & Shrub Protect & Feed (64 oz) | Year-round infestation prevention with plant nutrition | Up to 12 months |
| Bonide Annual Tree & Shrub Insect Control (128 oz) | Season-long protection with root-system movement | Up to 12 months |
| BioAdvanced 3-in-1 Insect, Disease, and Plant Mite Control (32 oz) | Integrated control for insects, diseases, and mites | Up to 30 days |
| Fertilome Tree & Shrub Drench (1 gal) | Systemic protection through root uptake for multiple pests | Up to 12 months |
BioAdvanced Tree & Shrub Insect Killer

Brand: Bayer Advanced
What it is best for: This ready-to-spray insect killer is best for quick, contact-kill control of listed pests on trees and shrubs. Suitable for home landscapes just beginning to experience insect activity.
Why chosen: It provides fast action and a relatively simple application with a short reapplication window, which helps when pests surge mid-season.
Limitations: Effectiveness is typically shorter-term; reapplication every couple of weeks may be needed during peak pest pressure. Not a long-term systemic feeder.
BioAdvanced 12 Month Tree & Shrub Protect & Feed Concentrate

Brand: Bayer Advanced
What it is best for: A comprehensive option for homeowners seeking both pest protection and plant nutrition over an extended period—ideally for established landscapes with multiple trees and shrubs.
Why chosen: It provides up to 12 months of protection from a range of listed insects while delivering slow-release fertilizer to support tree and shrub health.
Limitations: Requires proper mixing and application to ensure even distribution; heavy infestations may require supplementary measures.
Bonide Annual Tree & Shrub Insect Control with Systemaxx

Brand: Bonide
What it is best for: Ideal for lawns and gardens needing systemic movement from roots to foliage, especially on fruiting and ornamental trees.
Why chosen: The Systemaxx formulation allows the insecticide to move through the root zone, providing protection for new growth and longer-lasting suppression of listed pests.
Limitations: Being a concentrate, correct mixing is essential; misdosing can reduce effectiveness and may impact non-target plants if not applied properly.
BioAdvanced 3-in-1 Insect, Disease, and Plant Mite Control

Brand: Bayer Advanced
What it is best for: A versatile spray for outdoor plants that must combat pests, diseases, and mites in a single treatment.
Why chosen: Combines three protective actions in one product, reducing the need for separate treatments when pests and diseases occur together.
Limitations: Effect duration can be shorter—up to 30 days—so periodic reapplication may be necessary during active seasons.
Fertilome Tree & Shrub Drench

Brand: ferti-lome
What it is best for: Best for gardeners who prefer systemic protection through soil delivery to reach both established trees and new plantings.
Why chosen: Provides long-term protection via root uptake, supporting ongoing defense against a broad spectrum of insects for up to a year.
Limitations: Requires proper soil penetration and moisture to activate; effectiveness depends on application timing relative to tree growth cycles.
Buying Guide: Key Purchase Considerations
- Target pests: Identify the insects common to your area (aphids, beetles, borers, scale, mites) to pick a product formulated for those threats.
- Protection duration: Choose products with the duration you need—short bursts for acute outbreaks or year-long protection for maintenance.
- Delivery method: Surface sprays are quick; systemic drenches and soils ensure movement to new growth and roots.
- Plant health support: Some options combine pest control with plant nutrition, which can bolster resilience in stressed trees and shrubs.
- Safety and labeling: Always follow label directions regarding application timing, water hardness, and compatibility with other garden products.
- Site considerations: Consider size and maturity of trees/shrubs; larger trees may benefit from systemic formulations or soil drenches for deep protection.
Frequently Asked Questions
- What is the difference between contact and systemic pest controls?
Answer: Contact controls kill pests on contact and often require reapplication; systemic controls are taken up by the plant and provide longer-lasting protection, including new growth. - Can I combine a pest control product with fertilizer?
Answer: Some products are designed to also feed plants, but always read the label for compatibility and timing to avoid phytotoxicity. - Which product is best for a year-round protection plan?
Answer: Products labeled for 12-month protection are designed to prevent new infestations for up to a year when applied correctly. - Should I treat fruiting trees differently than ornamentals?
Answer: Fruiting trees may require products that control pests common to fruit crops; ensure the product label lists edible crops if you plan to harvest. - Is a ready-to-spray product better for quick action?
Answer: Ready-to-spray offers rapid knockdown of listed pests, useful for sudden outbreaks, but may require more frequent applications. - What safety steps are important during application?
Answer: Wear protective clothing, apply on calm days to prevent drift, and keep children and pets away from treated areas until dry.